IVF/ICSI efficiency in women with Hashimoto thyroiditis

Авторы

  • Галина Сафарян St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation
  • Александр Гзгзян St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation ; D.O.Ott Research Institute of Obstetrics, Gynecology and Reproductology, 3, Mendeleevskaya lin., St. Petersburg, 199034, Russian Federation
  • Ляиля Джемлиханова 1 St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation ; D.O.Ott Research Institute of Obstetrics, Gynecology and Reproductology, 3, Mendeleevskaya lin., St. Petersburg, 199034, Russian Federation https://orcid.org/0000-0001-6842-4430
  • Дарико Ниаури St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation ; D.O.Ott Research Institute of Obstetrics, Gynecology and Reproductology, 3, Mendeleevskaya lin., St. Petersburg, 199034, Russian Federation

DOI:

https://doi.org/10.21638/spbu11.2019.431

Аннотация

It is known that in women affected with thyroid autoimmunity, namely Hashimoto’s thyroiditis, the prevalence of infertility is very high and reaches 47%. The retrospective cohort study was performed to assess the effects of thyroid autoimmunity on IVF/ICSI outcomes in women with infertility due to tubal factor and verified autoimmune thyroiditis in status of euthyroidism. The present study confirms a negative impact of thyroid autoimmunity on the course of pregnancy achieved through IVF/ICSI. Thyroid autoimmunity does not appear to have an impact on IVF/ICSI outcome in terms of mean number of oocytes retrieved. However, fertilization, implantation and delivery rates were lower, and the risk of miscarriage was higher in the presence of anti-thyroperoxidase autoantibodies. Thus, thyroid autoanantibodies positivity even in euthyroid state should be considered an independent risk factor for pregnancy complications after IVF/ICSI treatment.

Ключевые слова:

TPOAbs, ART, infertility, ovarian reserve, embryo qualit

Скачивания

Данные скачивания пока недоступны.
 

Биография автора

Ляиля Джемлиханова, 1 St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation ; D.O.Ott Research Institute of Obstetrics, Gynecology and Reproductology, 3, Mendeleevskaya lin., St. Petersburg, 199034, Russian Federation

 

Библиографические ссылки


References

Kuharić M., Rozić D., Karner I. Thyroid Autoimmunity and Infertility. SEEMEDJ, 2017, vol. 1, no. 2, pp. 1–10.

Perminova S.G. Infertility in women with thyroid disease: Principles of diagnosis, management. Akusherstvo i ginekologiia: Novosti. Mneniia. Obuchenie, 2013, no. 2, pp. 18–24. (In Russian)

Shoenfeld Y., Meroni P.L., Churilov L.P. (Eds). Guide in Autoimmune Diseases for General Medical Practice. St. Petersburg, ELBI-Medkniga Publ., 2017, pp. 298–323.

Quintino-Moro A., Zantut-Wittmann D.E., Tambascia M., Machado H.D.C., Fernandes A. High Prevalence of Infertility among Women with Graves’ Disease and Hashimoto’s Thyroiditis.Int. J. Endocrinol., 2014, vol. 2014, Article ID 982705.

Загрузки

Опубликован

15.06.2020

Как цитировать

Сафарян, Г., Гзгзян, А., Джемлиханова, Л., & Ниаури, Д. (2020). IVF/ICSI efficiency in women with Hashimoto thyroiditis. Вестник Санкт-Петербургского университета. Медицина, 14(4), 374–376. https://doi.org/10.21638/spbu11.2019.431

Выпуск

Том 14 № 4 (2019)

Раздел

Акушерство и гинекология

Лицензия

Статьи журнала «Вестник Санкт-Петербургского университета. Медицина» находятся в открытом доступе и распространяются в соответствии с условиями Лицензионного Договора с Санкт-Петербургским государственным университетом, который бесплатно предоставляет авторам неограниченное распространение и самостоятельное архивирование.

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