НЕГАТИВНЫЕ ЭФФЕКТЫ ТРАНСПЛАНТАЦИИ АУТОЛОГИЧНОЙ ЖИРОВОЙ ТКАНИ, ОБОГАЩЕННОЙ КУЛЬТУРОЙ СТВОЛОВЫХ КЛЕТОК (ОБЗОР ЛИТЕРАТУРЫ)

Авторы

  • Николай Сергеевич Романенков Медицинский информационно-аналитический центр, Российская Федерация, 198095, Санкт-Петербург, ул. Шкапина, 30, лит. А
  • Константин Николаевич Мовчан Медицинский информационно-аналитический центр, Российская Федерация, 198095, Санкт-Петербург, ул. Шкапина, 30, лит. А ;Северо-Западный государственный медицинский университет им. И. И. Мечникова, Российская Федерация, 191015, Санкт-Петербург, ул. Кирочная, 41

DOI:

https://doi.org/10.21638/11701/spbu11.2017.403

Аннотация

Представлены сведения специалистов в области пластической, реконструктивной и эстетической хирургии, исследовавших риски развития и структуру осложнений клеточной терапии на этапе как сбора биологического материала для выделения стволовых клеток, так и их последующей трансплантации. Анализ данных многих авторов позволяет считать, что даже при минимальной инвазивности хирургических вмешательств на этапах осуществления клеточно-связанного липотрансфера выполнение этих операций все же сопряжено с возможностью развития ряда осложнений, в том числе и при их осуществлении соматически здоровым пациентам по эстетическим показаниям. Частота развития осложнений, представляющих угрозу для жизни, при клеточно-вязанном липотрансфере варьирует от 0,02 до 0,3 %. Очевидно, что проведение хирургических вмешательств в формате клеточной терапии должно осуществляться исключительно по показаниям с учетом данных клинического обследования пациентов до трансплантации стволовых клеток. Для предупреждения осложнений клеточносвязанного липотрансфера в послеоперационном периоде необходимо скрупулезное соблюдение правил асептики и антисептики, методики выполнения хирургических вмешательств, комплексной профилактики (независимо от объема операции) тромботических осложнений, целенаправленной компенсационной коррекции сопутствующей патологии пациента.Библиогр. 70 назв.

Ключевые слова:

пластическая хирургия, осложнения операций, мезенхимальные стволовые клетки, жировая ткань

Скачивания

 

Библиографические ссылки


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Загрузки

Опубликован

05.12.2017

Как цитировать

Романенков, Н. С., & Мовчан, К. Н. (2017). НЕГАТИВНЫЕ ЭФФЕКТЫ ТРАНСПЛАНТАЦИИ АУТОЛОГИЧНОЙ ЖИРОВОЙ ТКАНИ, ОБОГАЩЕННОЙ КУЛЬТУРОЙ СТВОЛОВЫХ КЛЕТОК (ОБЗОР ЛИТЕРАТУРЫ). Вестник Санкт-Петербургского университета. Медицина, 12(4), 326–339. https://doi.org/10.21638/11701/spbu11.2017.403

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Хирургия

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