ТКАНЕВЫЕ МАТРИЦЫ КЛАПАНОВ СЕРДЦА: СОСТОЯНИЕ ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ
DOI:
https://doi.org/10.21638/11701/spbu11.2016.206Аннотация
Первые успешные протезирования аортального и митрального клапанов сердца были выполнены в 1960 г. соответственно D. Harken и N. Braunwald. В обоих случаях использовались механические протезы, однако спустя всего 10 лет M. Ionescu впервые имплантировал первый биологический клапан человеку. В ходе эволюции биологических клапанных протезов хирургами использовались свиные аортальные, ксеноперикардиальные протезы и человеческие аллографты (свежие и криосохраненные), а в последние полтора десятилетия на вооружение были взяты тканевая инженерия и направленная регенерация тканей. В настоящей статье описаны основные проблемы этой области, проведена сравнительная характеристика различных методик децеллюляризации полулунных клапанов, а также перспективы использования тканевой инженерии для создания атриовентрикулярных клапанных заменителей. Библиогр. 73 назв. Ил. 1.
Ключевые слова:
тканевая инженерия, направленная регенерация, децеллюляризация, децеллюляризированный клапан сердца, тканевая матрица
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Опубликован
07.10.2016
Как цитировать
Яблонский, П. П., Чеботарь, С., Тудорахе, И., & Хаверих, А. (2016). ТКАНЕВЫЕ МАТРИЦЫ КЛАПАНОВ СЕРДЦА: СОСТОЯНИЕ ПРОБЛЕМЫ И ПЕРСПЕКТИВЫ. Вестник Санкт-Петербургского университета. Медицина, 11(2), 51–61. https://doi.org/10.21638/11701/spbu11.2016.206
Выпуск
Раздел
Кардиология
Лицензия
Статьи журнала «Вестник Санкт-Петербургского университета. Медицина» находятся в открытом доступе и распространяются в соответствии с условиями Лицензионного Договора с Санкт-Петербургским государственным университетом, который бесплатно предоставляет авторам неограниченное распространение и самостоятельное архивирование.
