ВЛИЯНИЕ МУКОАКТИВНЫХ ПРЕПАРАТОВ НА СОСТОЯНИЕ НЕСПЕЦИФИЧЕСКИХ ПРОТЕИНАЗ И ИХ ИНГИБИТОРОВ У БОЛЬНЫХ ОСТРЫМ КАТАРАЛЬНЫМ РИНОСИНУСИТОМ

Anton Zavalii; Anatoliy Kubyshkin; Anna Zhukova

doi:10.21638/11701/spbu11.2016.405

Authors

Anton Zavalii S. I. Georgievsky Medical Academy of V. I. Vernadsky Crimean Federal University, Republic of Crimea, 295006, Simferopol, Lenina bul., 5/7
Anatoliy Kubyshkin S. I. Georgievsky Medical Academy of V. I. Vernadsky Crimean Federal University, Republic of Crimea, 295006, Simferopol, Lenina bul., 5/7
Anna Zhukova S. I. Georgievsky Medical Academy of V. I. Vernadsky Crimean Federal University, Republic of Crimea, 295006, Simferopol, Lenina bul., 5/7

DOI:

https://doi.org/10.21638/11701/spbu11.2016.405

Abstract

The study was conducted in three groups of patients (45 subjects) with acute catarrhal rhinosinusitis using mucoactive agents as a part of treatment. It has been established that this pathology is characterized by an acute-phase increase of antitrypsin activity in the blood serum and sinonasal discharge. Comparative analysis of the results obtained aft er applying various groups of mucoactive agents has demonstrated that BNO-101 has greater eff ect in this type of infl ammation; it decreased the activity of elastase and trypsin-like proteases while normalizing clinical symptoms and the activity of proteinase inhibitors in the sinonasal discharge. Refs 12.Table 1.

Keywords:

acute catarrhal infl ammation, rhinosinusitis, mucoactive agents, proteinases, proteinase inhibitors

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References

Литература

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