ULTRASTRUCTURAL CHANGES OF KIDNEY DURING EXPERIMENTALLY MODELED THERMAL ISCHEMIA

Authors

  • Сергей Валерьевич Попов St. Luka Clinical Hospital, 46, Chugunnaya ul., St. Petersburg, 194044, Russian Federation
  • Руслан Гусейнович Гусейнов St. Luka Clinical Hospital, 46, Chugunnaya ul., St. Petersburg, 194044, Russian Federation
  • Андрей Николаевич Горшенин St. Luka Clinical Hospital, 46, Chugunnaya ul., St. Petersburg, 194044, Russian Federation
  • Константин Владимирович Сивак St. Luka Clinical Hospital, 46, Chugunnaya ul., St. Petersburg, 194044, Russian Federation
  • Петр Казимирович Яблонский St. Luka Clinical Hospital, 46, Chugunnaya ul., St. Petersburg, 194044, Russian Federation
  • Олег Николаевич Скрябин St. Luka Clinical Hospital, 46, Chugunnaya ul., St. Petersburg, 194044, Russian Federation
  • Татьяна Ивановна Виноградова St. Luka Clinical Hospital, 46, Chugunnaya ul., St. Petersburg, 194044, Russian Federation

Abstract

Nowadays the laparoscopic kidney resection is a “gold standard” for treatment of tumor stages T1–2a.
One of the most important factors is kidney thermal ischemia leading to ischemic and reperfusion damage. It’s of current importance to elaborate a nephron-sparing complex end create an eff ective algorithm for preoperative, operative and post-operative periods. Th e key problem is a choice of time interval for renal artery clamping during operation, which will not cause irreversible structural and functional kidney changes. Th e purpose of this experimental study is a detection of maximum safe time of ischemia with morphologic verifi cation via electronic microscopy. Study results show that kidney epithelium keeps vitality in 30 minutes and 60 minutes of ischemia. In 90 minutes it has irreversible cells damage (necrosis). Th erefore “the point of no return” for kidney epithelium is beyond one hour interval of thermal ischemia. In combination with eff ective pharmacologic protection this fact expands the opportunities of modern laparoscopic surgery. Refs17. Figs 8.

Keywords:

kidney thermal ischemia, electronic microscopy, malpighian tuft, ischemia reperfusion syndrome

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References

Литература

Nix, S., Smith M., Vicenzino B. Prevalence of hallux valgus in the general population: a systematic review and meta-analysis // Journal of Foot and Ankle Research. 2010. N 3. P. 21.

Roddy, E. Zhang W., Doherty M. Prevalence and associations of hallux valgus in a primary care population // Arthritis & Rheumatism (Arthritis Care & Research). 2008. Vol. 59, N 6. P. 857–862.

Gallentine, J. W. Deorio J. K., Deorio M. J. Bunion surgery using locking-plate fi xation of proximal metatarsal chevron osteotomies // Foot Ankle International. 2007. N 28 (3). P. 361–368.

Fakoor M., Sarafan N., Mohammadhoseini P., Khorami M., Arti H., Mosavi S., Aghaeeaghdam A.Comparison of Clinical Outcomes of Scarf and Chevron Osteotomies and the McBride Procedure in the Treatment of Hallux Valgus Deformity // Archives of Bone and Joint Surgery. 2014. Mart. N 2(1).

P. 31–36.

Vopat B. G., Lareau C. R., Johnson J., Reinert S. E., DiGiovanni C. W. Comparative study of scarf and extended chevron osteotomies for correction of hallux valgus // Foot and Ankle Specialist. 2013. N 6 (6). P. 409–416.

Smith S. E., Landorf K. B., Butterworth P. A., Menz H. B. Scarf versus chevron osteotomy for the correction of 1–2 intermetatarsal angle in hallux valgus: a systematic review and meta-analysis // The Journal of Foot and Ankle Surgery. 2012. N 51 (4). P. 437–444.

Martínez-Nova A., Sánchez-Rodríguez R., Gómez-Martín B., Escamilla E. Martínez,Expósito-Arcas A., Novel-Martí V. The eff ect of adductor tendon transposition in the modifi ed McBride procedure // Foot and Ankle Specialist. 2008. N 1 (5). P. 275–279.

Mann R. A. Hallux valgus and complications of hallux valgus / R. A. Mann, M. J. Coughlin // Mann R. A, editor: Surgery of the foot, St Louis, CV Mosby, 1986. P. 167–296.

Минасов, Б. Ш., Гутов С. П., Билялов А. Р. Способ реконструкции переднего отдела стопы при вальгусной деформации I пальца // Травматология и ортопедия России. 2007. № 2. С. 84–88.

Jolly G. P. Hallux abducto valgus and surgery of the fi rst ray / eds L. A. Levy, V. J. Hetherington. Principles and Practice of Podiatric Medicine. Churchill Livingstone, New York, 1990. 823 p.

Jardé O., Trinquier-Lautard J. L., Meire P., Gabrion A., Vives P. Treatment of hallux valgus by varus osteotomy of the fi rst phalanx associated with adductor plasty. [Article in French] // Revue de Chirurgie Orthopédique et Réparatrice de l’Appareil Moteur. 1996. N 82 (6). P. 541–548.

Vega M. R., Jackson-Smith J. L. A variable fi rst metatarsal distal “L” osteotomy with adductor tendon transfer // Th e Journal of Foot and Ankle Surgery. 1995. N 34 (4). P. 384–388.

Granberry W. M., Hickey C. H. Hallux valgus correction with metatarsal osteotomy: eff ect of a lateral distal soft tissue procedure // Foot Ankle International. 1995. N 16 (3). P. 132–138.

Карданов А. А., Загородний Н. В., Макинян Л. Г., Лукин М. П. Наш опыт хирургического лечения вальгусного отклонения первого пальца стопы посредством остеотомии SCARF // Травматология и ортопедия России. 2008. № 2. С. 437–431.

Resch S., Stenström A., Reynisson K., Jonsson K. Chevron osteotomy for hallux valgus not improved by additional adductor tenotomy. A prospective, randomized study of 84 patients // Acta Orthopaedica Scandinavica. 1994. N 65. P. 541–544.

Havlícek V., Kovanda M., Kunovský R. Surgical management of hallux valgus by techniques preserving the first metatarsophalangeal joint: long-term results [Article in Czech] // Acta chirurgiae orthopaedicaeet traumatologiae Cechoslovaca. 2007. N 74 (2). P. 105–110.

Steck J. K., Ringstrom J. B. Long Z-osteotomy: a review and new modifi cation to correct troughing // The Journal of Foot and Ankle Surgery. 2001. N 40 (5). P. 305–310.

Бойченко А. В., Соломин Л. Н., Парфеев С. Г., Обухов И. Э., Белокрылова М. С., Пашукова Т. А.Сравнение результатов односторонней и двусторонней хирургической коррекции hallux valgus. Травматология и ортопедия России. 2014. № 3 (73). С. 44–51.


References

Nix, S., Smith M., Vicenzino B. Prevalence of hallux valgus in the general population: a systematic review and meta-analysis. Journal of Foot and Ankle Research, 2010, no. 3, 21 p.

Roddy, E. Zhang W., Doherty M. Prevalence and associations of hallux valgus in a primary care population. Arthritis & Rheumatism (Arthritis Care & Research), 2008, vol. 59, no. 6, pp. 857–862.

Gallentine, J. W. Deorio J. K., Deorio M. J. Bunion surgery using locking-plate fi xation of proximal metatarsal chevron osteotomies. Foot Ankle International, 2007, no. 28 (3), pp. 361–368.

Fakoor M., Sarafan N., Mohammadhoseini P., Khorami M., Arti H., Mosavi S., Aghaeeaghdam A. Comparison of Clinical Outcomes of Scarf and Chevron Osteotomies and the McBride Procedure in the Treatment of Hallux Valgus Deformity. Archives of Bone and Joint Surgery, 2014, Mart, no. 2 (1),pp. 31–36.

Vopat B. G., Lareau C. R., Johnson J., Reinert S. E., DiGiovanni C. W. Comparative study of scarf and extended chevron osteotomies for correction of hallux valgus. Foot and Ankle Specialist, 2013, no. 6 (6),pp. 409–416.

Smith, S. E., Landorf K. B., Butterworth P. A., Menz H. B. Scarf versus chevron osteotomy for the correction of 1–2 intermetatarsal angle in hallux valgus: a systematic review and meta-analysis.The Journal

of Foot and Ankle Surgery, 2012, no. 51 (4), pp. 437–444.

Martínez-Nova A., Sánchez-Rodríguez R., Gómez-Martín B., Escamilla E. Martínez, Expósito-Arcas A., Novel-Martí V. Th e eff ect of adductor tendon transposition in the modifi ed McBride procedure.Foot and Ankle Specialist, 2008, no. 1 (5), pp. 275–279.

Mann R. A. Hallux valgus and complications of hallux valgus. R. A. Mann, M. J. Coughlin. Mann R. A, editor: Surgery of the foot, St Louis, CV Mosby, 1986, pp. 167–296.

Minasov, B. Sh., Gutov S. P., Bilialov A. R. Sposob rekonstruktsii perednego otdela stopy pri val’gusnoi deformatsii I pal’tsa [Th e New method of forefoot reconstruction in patients with hallux valgus]. Travmatologiia i ortopediia Rossii [Traumatology and orthopedics Russia], 2007, no. 2, pp. 84–88. (In Russian)

Jolly G. P. Hallux abducto valgus and surgery of the fi rst ray. Eds L. A. Levy, V. J. Hetherington. Principles and Practice of Podiatric Medicine. Churchill Livingstone, New York, 1990. 823 p.

Jardé O., Trinquier-Lautard J. L., Meire P., Gabrion A., Vives P. Treatment of hallux valgus by varus osteotomy of the fi rst phalanx associated with adductor plasty. [Article in French]. Revue de Chirurgie Orthopédique et Réparatrice de l’Appareil Moteur, 1996, no. 82 (6), pp. 541–548.

Vega M. R., Jackson-Smith J. L. A variable fi rst metatarsal distal “L” osteotomy with adductor tendon transfer. The Journal of Foot and Ankle Surgery, 1995, no. 34 (4), pp. 384–388.

Granberry W. M., Hickey C. H. Hallux valgus correction with metatarsal osteotomy: eff ect of a lateral distal soft tissue procedure. Foot Ankle International, 1995, no. 16 (3), pp. 132–138.

Kardanov A. A., Zagorodnii N. V., Makinian L. G., Lukin M. P. Nash opyt khirurgicheskogo lecheniia val’gusnogo otkloneniia pervogo pal’tsa stopy posredstvom osteotomii SCARF [Our experience of hallux valgus surgical treatment by scarf osteotomy]. Travmatologiia i ortopediia Rossii [Traumatology and orthopedics Russia], 2008, no. 2, pp. 437–431. (In Russian)

Resch S., Stenström A., Reynisson K., Jonsson K. Chevron osteotomy for hallux valgus not improved by additional adductor tenotomy. A prospective, randomized study of 84 patients. Acta Orthopaedica Scandinavica, 1994, no. 65, pp. 541–544.

Havlícek V., Kovanda M., Kunovský R. Surgical management of hallux valgus by techniques preserving the first metatarsophalangeal joint: long-term results [Article in Czech]. Acta chirurgiae orthopaedicaeet traumatologiae Cechoslovaca, 2007, no. 74 (2), pp. 105–110.

Steck J. K., Ringstrom J. B. Long Z-osteotomy: a review and new modifi cation to correct troughing.The Journal of Foot and Ankle Surgery, 2001, no. 40 (5), pp. 305–310.

Boichenko A. V., Solomin L. N., Parfeev S. G., Obukhov I. E., Belokrylova M. S., Pashukova T. A. Sravnenie rezul’tatov odnostoronnei i dvustoronnei khirurgicheskoi korrektsii hallux valgus [Comparison of unilateral and bilateral surgical correction of hallux valgus]. Travmatologiia i ortopediia Rossii [Traumatology and orthopedics Russia], 2014, no. 3 (73), pp. 44–51. (In Russian)

Published

2016-07-07

How to Cite

Попов, С. В., Гусейнов, Р. Г., Горшенин, А. Н., Сивак, К. В., Яблонский, П. К., Скрябин, О. Н., & Виноградова, Т. И. (2016). ULTRASTRUCTURAL CHANGES OF KIDNEY DURING EXPERIMENTALLY MODELED THERMAL ISCHEMIA. Vestnik of Saint Petersburg University. Medicine, 11(1), 104–119. Retrieved from https://medicine-journal.spbu.ru/article/view/6031

Issue

Section

Urology

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