Urbanization-related factors as triggers of the development of type 1 diabetes mellitus*

Авторы

  • Лидия Сопрун St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation
  • Игорь Акулин St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation
  • Владимир Утехин St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation
  • Антон Гвоздетский St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation
  • Леонид Чурилов St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation ;St. Petersburg Research Institute of Phthisiopulmonology, Health Ministry of Russia, 2–4, Ligovskiy pr., St. Petersburg, 191036, Russian Federation

DOI:

https://doi.org/10.21638/spbu11.2019.421

Аннотация

The proportion of autoimmune pathology increases along with urbanization. A cohort retrospective prospective study was performed to analyze the prevalence of type I diabetes mellitus in 83 regions of the Russian Federation during the period from 2008 to 2017 and the influence of urbanization factors on type I diabetes mellitus incidence. The main urbanistic factor obtained during mathematical modeling contributing to the development and distribution of the incidence of type I diabetes mellitus is air pollution with solid dust particles, namely air emissions from the stationary sources, highways density and the number of buses. The urbanization factors are controlled and, therefore, many of the adverse effects on human health can be prevented by using organizational and methodological recommendations as well as new regulations on air pollutants.

Ключевые слова:

geoepidemiology, autoimmune diseases, pollutions, type I diabetes mellitus, urbanization, solid dust particles

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Библиографические ссылки


References

Shoenfeld Y., Meroni P.L., Churilov L.P.Guide to Autoimmune Diseases for General Medical Practice.St. Petersburg, Medkniga-ELBI Publ., 2017. (In Russian)

Di Ciaula A. Type I diabetes in paediatric age in Apulia (Italy): Incidence and associations with outdoor air pollutants. Diabetes Res. Clini. Practice, 2016, no. 111, pp. 36–43.

Gao B. et al. Multiomics reveals that lead exposure disturbs gut microbiome development, key metabolites, and metabolic pathways.Chem. Res. Toxicol., 2017, no. 30, pp. 996–1005.

Gawda A., Majka G. Air pollution, oxidative stress, and exacerbation of autoimmune diseases.Central European Journal of Immunology, 2017,no. 42, pp. 305–312.

Shukla A., Bunkar N. Air pollution associated epigenetic modifications: Transgenerational inheritance and underlying molecular mechanisms. Epidemiology, 2019, no. 656, pp. 760–777.

Загрузки

Опубликован

15.06.2020

Как цитировать

Сопрун, Л., Акулин, И., Утехин, В., Гвоздетский, А., & Чурилов, Л. (2020). Urbanization-related factors as triggers of the development of type 1 diabetes mellitus*. Вестник Санкт-Петербургского университета. Медицина, 14(4), 340–342. https://doi.org/10.21638/spbu11.2019.421

Выпуск

Том 14 № 4 (2019)

Раздел

Внутренние болезни

Лицензия

Статьи журнала «Вестник Санкт-Петербургского университета. Медицина» находятся в открытом доступе и распространяются в соответствии с условиями Лицензионного Договора с Санкт-Петербургским государственным университетом, который бесплатно предоставляет авторам неограниченное распространение и самостоятельное архивирование.

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