Psoriatic arthritis: current state of the problemPsoriatic arthritis: Current state of the problem
DOI:
https://doi.org/10.21638/spbu11.2019.302Аннотация
The article presents data on the prevalence, pathogenesis, clinical picture, diagnosis, treatment of psoriatic arthritis (PsA). Despite significant scientific advances, this pathology remains a serious medical and social problem. The etiology and pathogenesis of PsA are not fully understood. It leads to imperfect treatment methods. Given the polymorphism of clinical picture, as well as the lack of specific laboratory parameters, the diagnosis of PsA, especially at early stage, presents considerable difficulties. It is necessary to remember about the possibility ofdeveloping such socially significant comorbid conditions as hypertension, ischemic heart disease,type 2 diabetes, obesity, metabolic syndrome, inflammatory bowel disease, eye damage in patients with PsA. The pathology of the nails in patients with psoriasis and its relationship with the development and course of PsA is particularly interesting. The progressive nature of the damage to the musculoskeletal system, leading to a decreased function of the joints, disability, and impaired social adaptation, therefore the early diagnosis of PsA and the choice of optimal therapy are current priorities. A multidisciplinary approach to the management of PsA patients will facilitate the timely detection of pathology, as well as improve the quality of life of patients and the outcome of the disease.
Ключевые слова:
psoriasis, psoriatic arthritis, enthesitis, comorbidity, nail damage
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Статьи журнала «Вестник Санкт-Петербургского университета. Медицина» находятся в открытом доступе и распространяются в соответствии с условиями Лицензионного Договора с Санкт-Петербургским государственным университетом, который бесплатно предоставляет авторам неограниченное распространение и самостоятельное архивирование.