Современное представление об участии метаболических нарушений в кардиоренальных взаимоотношениях

Антон Олегович Иванов; Александр Николаевич Шишкин

doi:10.21638/11701/spbu11.2018.301

Авторы

Антон Олегович Иванов Санкт-Петербургский государственный университет, Российская Федерация, 199034, Санкт-Петербург, Университетская наб., 7–9
Александр Николаевич Шишкин Санкт-Петербургский государственный университет, Российская Федерация, 199034, Санкт-Петербург, Университетская наб., 7–9

DOI:

https://doi.org/10.21638/11701/spbu11.2018.301

Аннотация

В обзоре представлены последние данные об участии метаболических нарушений в кардиоренальных взаимоотношениях, современное понимание кардиоренального синдрома и его факторов риска, хорошо известных и малоизученных общих звеньев патогенеза почечных и сердечно-сосудистых заболеваний. Особое внимание уделено таким факторам риска, как ожирение, дислипидемия, артериальная гипертензия, микроальбуминурия у пациентов с хронической болезнью почек и хронической сердечной недостаточностью. Определение ранних и достоверных предикторов кардиоренального синдрома среди метаболических нарушений крайне важно в связи с интенсивным ростом числа пациентов с данными нарушениями.

Ключевые слова:

кардиоренальный синдром, метаболический синдром, артериальная гипертензия, хроническая сердечная недостаточность, хроническая болезнь почек, микроальбуминурия

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Библиографические ссылки

Литература

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Bonnet F., Marre M., Halimi J. M., Stengel B., Lange C., Laville M., Tichet J., Balkau B. Waist circumference and the metabolic syndrome predict the development of elevated albuminuria in non-diabetic subjects: the DESIR Study. Hypertens, 2006, no. 24, pp. 1157–1163.

Tozawa M., Iseki C., Tokashiki K., Chinen S., Kohagura K., Kinjo K., Takishita S., Iseki K. Metabolic syndrome and risk of developing chronic kidney disease in Japanese adults. Hypertens. Res., 2007, no. 30, pp. 937–943.

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Ryu S., Chang Y., Woo H. Y., Lee K. B., Kim S. G., Kim D. I., Kim W.S., Suh B. S., Jeong C., Yoon K. Time-dependent association between metabolic syndrome and risk of CKD in Korean men without hypertension or diabetes. Amer. J. Kidney Dis., 2009, no. 53, pp. 59–69.

Watanabe H., Obata H., Watanabe T., Sasaki S., Nagai K., Aizawa Y. Metabolic syndrome and risk of development of chronic kidney disease: the Niigata preventive medicine study. Diabetes Metab Res Rev., 2010, no. 26, pp. 26–32.

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Verbrugge F. H., Dupont M., Steels P., Grieten L., Swennen Q., Tang W. H. et al. The kidney in congestive heart failure: are natriuresis, sodium, and diuretics really the good, the bad and the ugly? Eur. J. Heart Fail., 2014, no. 16, pp. 133–142.

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Frederik Hendrik Verbrugge, Lars Grieten and Wilfried Mullensa. Management of the Cardiorenal Syndrome in Decompensated Heart Failure. Cardiorenal Med., 2014, Dec., no. 4 (3–4), pp. 176–188.

Herzog C. A., Asinger R. W., Berger A. K., Charytan D. M., Diez J., Hart R. G. et al. Cardiovascular disease in chronic kidney disease. A clinical update from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int., 2011, no. 80, pp. 572–586.

Ahmed M. S., Wong C. F., Pai P. Cardiorenal syndrome — a new classification and current evidence on its management. Clin. Nephrol., 2010, Oct., no. 74 (4), pp. 245–57.

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