DIFFERENT ENDOSCOPIC TREATMENT OPTIONS IN THE MANAGEMENT OF ACHALASIA

Authors

  • Михаил Павлович Королев City Mariinsky hospital, 56, Liteinyi pr., St. Petersburg, 194104, Russian Federation
  • Леонид Евгеньевич Федотов City Mariinsky hospital, 56, Liteinyi pr., St. Petersburg, 194104, Russian Federation
  • Юрий Александрович Спесивцев City Mariinsky hospital, 56, Liteinyi pr., St. Petersburg, 194104, Russian Federation
  • Александр Леонидович Оглоблин City Mariinsky hospital, 56, Liteinyi pr., St. Petersburg, 194104, Russian Federation
  • Александр Александрович Смирнов City Mariinsky hospital, 56, Liteinyi pr., St. Petersburg, 194104, Russian Federation
  • Шохрат Девлат оглы Мамедов City Mariinsky hospital, 56, Liteinyi pr., St. Petersburg, 194104, Russian Federation
  • Евгений Владимирович Конанов City Mariinsky hospital, 56, Liteinyi pr., St. Petersburg, 194104, Russian Federation

DOI:

https://doi.org/10.21638/11701/spbu11.2016.203

Abstract

In this article, we showed the optimal examination schedule in patients with suspected achalasia. The
diagnostic algorithm of achalasia included X-ray, multispiral computed tomography (MSCT) of the chest and upper abdomen and endoscopic examination methods. All these methods allowed for establishing the exact diagnosis and precise stage of the disease. Th e most common classifi cation for achalasia staging in the Russian Federation is the classifi cation proposed by Petrovskiy B. V. in 1962 which is based on the interpretation of X-ray imaging results because of their simplicity and availability. In this study we also showed diff erent treatment options such as an endoscopic balloon pneumatic dilation used to relieve the obstruction by mechanical disrupting, botulinum toxin injection directed to reduce pressure of the lower esophageal sphincter, minimally invasive interventions with pharmacological therapy, and surgical treatment for patients with IV stage of the disease that may benefi t in 98,2% of those patients. Additionally we showed clinical results of an absolutely new treatment method of endoscopic managing achalasia in the Russian Federation: oral esophageal myotomy (POEM) used in our clinic since 2014. It is a promising and minimally invasive option for treating achalasia. However, it still requires more data and assessment of clinical effi cacy. Refs 19. Figs 8.

Keywords:

Achalasia, endoscopic balloon pneumatic dilation, botulinum toxin injection, peroral endoscopic myotomy (POEM)

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References

Литература

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References

Mikilicz J. R. Handb. der praktischen Chirurgie.

Hurst A. F., Rake G. W. Achalasia of the cardia. Q. S. Med., 1930, vol. 23, pp. 491–507.

Park W., Vaezi M. F. Etiology and pathogenesis of achalasia the current understanding. Am. J. Gastroenterol., 2005 Jun, vol. 100 (6), pp. 1404–1414.

Petrovskii B. V. Kardiospazm i ego khirurgicheskoe znachenie [Cardiospasm and its surgical signifi cance]. Trudy 27-go Vsesoiuznogo s’’ezda khirurgov. Moscow, 1962, pp. 162–173. (In Russian)

Boztas G., Mungan Z., Ozdil S., Akyuz F., Karaca C., Demir K., Kaymakoglu S., Cakaloglu Y., Okten A. Pneumatic balloon dilatation in primary achalasia: the long-term follow-up results. Hepatogastroenterology,2005 Mar-Apr, vol. 52 (62), pp. 475–480.

Beker K., Biesenbach S., Erckenbrecht J. F., Frieling T. Eff ct of balloon compliance on symptomatic success of pneumatic dilation in achalasia patients. Z. Gastroenterol., 2001 Oct, vol. 39 (10), pp. 831–836.

Chan K. C., Wong S. K., Lee D. W., Mui W. L., Chan A. C., Ng E. K., Wu J. C., Sung J. J., Chung S. C. Short-term and long-term results of endoscopic balloon dilation for ahalasia: 12 years experience. Endoscopy,2004 Aug, vol. 36 (8), pp. 690–694.

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Eckardt V. F., Gockrl I., Bernhard G. Pneumatic dilation for ahalasia: late results of a prospective follow up investigation. Gut., 2004, vol. 53, pp. 629–633.

Farhoomand K., Connor J. E., Richter J. E., Achkar E., Vaezi M. F. Predictors of outcome of pneumatic dilation in achalasia. Clin. Gastroentrol. Hepatol., 2004 May, vol. 2(5), pp. 389–394.

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Hungness E. Per oral Endoscopic Myotomy (POEM): Achalasia — Treatment optios and Expected oucomes. SAGES PG Course, 2012.

Von Renteln D., Inoue H., Minami H., Werner Y. B., Pace A., Kersten J. F., Much C. C., Schachschal G.,Mann O., Keller J., Fuchs K. H. Rsch T. Peroral endoscopic myotomy for the treatment of achalasia: a prospective single center study. Am. J. Gastroenterol., 2012 Mar, vol. 107(3), pp. 411–417.

Published

2016-10-07

How to Cite

Королев, М. П., Федотов, Л. Е., Спесивцев, Ю. А., Оглоблин, А. Л., Смирнов, А. А., Мамедов, Ш. Д. о., & Конанов, Е. В. (2016). DIFFERENT ENDOSCOPIC TREATMENT OPTIONS IN THE MANAGEMENT OF ACHALASIA. Vestnik of Saint Petersburg University. Medicine, 11(2), 20–28. https://doi.org/10.21638/11701/spbu11.2016.203

Issue

Section

Surgery