COGNITIVE IMPAIRMENT DUE TO ALCOHOL ABUSE: CURRENT STATUS OF RESEARCH

Authors

  • Uladzimir I. Pikirenia Belarusian State Medical University, 83, pr. Dzerzhinskogo, Minsk, 220116, Republic of Belarus
  • Ilya A. Fedotov Ryazan State Medical University, 9, ul. Vysokovoltnaya, Ryazan, 390026, Russian Federation
  • Olga D. Tuchina Peoples’ Friendship University of Russia, 6, ul. Miklukho-Maklaya, Moscow, 117198, Russian Federation
  • Andrei U. Kapytau Belarusian State Medical University, 83, pr. Dzerzhinskogo, Minsk, 220116, Republic of Belarus

DOI:

https://doi.org/10.21638/11701/spbu11.2017.306

Abstract

Alcohol abuse causes significant changes in cognitive functioning. These effects are related to the fact that ethanol and acetaldehyde, its first metabolite, affect the the brain’s neurotransmitter systems. Long-term abuse may lead to the dysexecutive syndrome (DES) exhibited through emotional, behavioral and cognitive symptoms. Alcohol has a specific dose-dependent effect on memory that serves as a block of memory consolidation, i.e. transition of the short-term memories to the long-term storage.This effect displays either as reversible amnesias of events from the alcohol abuse period (blackouts), or as an irreversible fixation amnesia within Korsakoff’s syndrome. Refs 34.

Keywords:

alcohol, amnesia, blackouts, dysexecutive syndrome

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References


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Вестник Санкт-Петербургского университета. Медицина

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Published

2017-09-01

How to Cite

Pikirenia, U. I., Fedotov, I. A., Tuchina, O. D., & Kapytau, A. U. (2017). COGNITIVE IMPAIRMENT DUE TO ALCOHOL ABUSE: CURRENT STATUS OF RESEARCH. Vestnik of Saint Petersburg University. Medicine, 12(3), 266–272. https://doi.org/10.21638/11701/spbu11.2017.306

Issue

Vol. 12 No. 3 (2017)

Section

Neurology. Neurosurgery. Psychiatry

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Articles of "Vestnik of Saint Petersburg University. Medicine" are open access distributed under the terms of the License Agreement with Saint Petersburg State University, which permits to the authors unrestricted distribution and self-archiving free of charge.