Современное состояние проблемы дифференциальной диагностики структурных поражений головного мозга у пациентов со СПИДом по данным МРТ (обзор литературы)

Александр Андреевич Дроздов; Владимир Максимович Черемисин; Ирина Григорьевна Камышанская; Алексей Авенирович Яковлев; Владимир Борисович Мусатов; Иван Павлович Федуняк; Оксана Ивановна Федуняк; Мария Николаевна Артемьева

doi:10.21638/11701/spbu11.2018.407

Authors

Александр Андреевич Дроздов St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation
Владимир Максимович Черемисин St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation ; St. Petersburg Mariinsky Hospital, 56, Liteyniy pr., St. Petersburg, 191014, Russian Federation
Ирина Григорьевна Камышанская St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation ; St. Petersburg Mariinsky Hospital, 56, Liteyniy pr., St. Petersburg, 191014, Russian Federation
Алексей Авенирович Яковлев St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation; S. P. Botkinn Clinical Infectious Disease Hospital 30, 3, ul. Mirgorodskaya, St. Petersburg, 191024, Russian Federation
Владимир Борисович Мусатов St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation;S. P. Botkinn Clinical Infectious Disease Hospital 30, 3, ul. Mirgorodskaya, St. Petersburg, 191024, Russian Federation
Иван Павлович Федуняк North-Western State Medical University named after I. I. Mechnikov, 47, Piskarevsky pr., St. Petersburg, 195067, Russian Federation, ; S. P. Botkinn Clinical Infectious Disease Hospital 30, 3, ul. Mirgorodskaya, St. Petersburg, 191024, Russian Federation
Оксана Ивановна Федуняк S. P. Botkinn Clinical Infectious Disease Hospital 30, 3, ul. Mirgorodskaya, St. Petersburg, 191024, Russian Federation
Мария Николаевна Артемьева S. P. Botkinn Clinical Infectious Disease Hospital 30, 3, ul. Mirgorodskaya, St. Petersburg, 191024, Russian Federation

DOI:

https://doi.org/10.21638/11701/spbu11.2018.407

Abstract

The current article is an up-to-date literature review of common brain lesions and their MRI semiotics among patients with AIDS. We present classic MRI signs of AIDS-associated lesions and the variability of presentation based on the method of magnetic resonance. We provide a detailed review of MRI imaging of lesions with mass-effect: toxoplasmosis, primary CNS lymphoma and neurotuberculosis. In this review, we present wide variability of radiological signs and typical patterns that are used for differential diagnosis between these conditions. In this article, we also review HIV associated brain lesions without mass effect as PML and HIV associated encephalopathy. We highlighted unique polymorphism of progressive multifocal leukoencephalopathy as this pathology might have variable contrast enhancement and can be present with or without the mass effect. We present data about the comparison of MRI and CT imaging in diagnosing of HIV-associated brain lesion. Assuming differences in MRI protocols in different hospitals here we describe minimal brain MRI protocol that allows obtaining optima radiological studies.

Keywords:

MRI, HIV, AIDS, brain, opportunistic infection, neurotuberculosis, PML, PLCNS

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Литература

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