Infectious complications in traumatology and orthopedics

Authors

  • Alexander Dulaev Pavlov First Saint Petersburg State Medical University, 6–8, ul. L’va Tolstogo, St. Petersburg, 197022, Russian Federation
  • Andrey Ovdenko Pavlov First St. Petersburg State Medical University, 6–8, ul. L’va Tolstogo, St. Petersburg, 197022, Russian Federation
  • Sergey Varzin St. Petersburg State University, 7–9, Universitetskaya nab., St. Petersburg, 199034, Russian Federation ; St. Petersburg Medico-Social Institute, 72а, Kondratevsky pr., St. Petersburg, 195271, Russian Federation
  • Dmitry Dulaev Pavlov First St. Petersburg State Medical University, 6–8, ul. L’va Tolstogo, St. Petersburg, 197022, Russian Federation

DOI:

https://doi.org/10.21638/spbu11.2024.405

Abstract

Infectious complications, as a result of osteosynthesis, are the result of microbes entering from the outside when the fracture area is opened, aseptic disorders during surgery, as well as when the wound heals with secondary tension. The degree of injury, the nature of osteosynthesis, surgery, drainage, and the absence of antibiotic prophylaxis contribute to necrosis of bone areas. Endogenous adhesion of microbes to the implant is also possible. The process can go beyond necrotized tissues with the development of a nasal infection, which is accompanied by the death of previously intact cellular structures and a clinically pronounced general reaction of the body. Microorganisms fast-ro are fixed on wound surfaces and pass into a biofilm form of growth, which cleans them from antibodies, host micro- and macrophages, as well as from antibiotics. This can be facilitated by the metal structure itself, which, by its presence, significantly violates local immunity. With external fixation, in case of violation of the technique of installing rods or conducting Kirchner spokes, bone and soft tissue burns can occur, followed by the development of chronic osteomyelitis. Removing them or re-conducting, prescribing
antibiotics and surgical treatment, as a rule, lead to the sanitation of the purulent focus. In osseous osteosynthesis, microorganisms spread along the metal and bone, forming a “dead bone sandwich.” We use the classification of infectious complications of injuries and injuries from
the Guidelines for Military Field Surgery (2013).

Keywords:

traumatology and orthopedics, bone fractures, infectious complications, implant- associated infection, surgical treatment, prevention

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References

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Published

2025-04-21

How to Cite

Dulaev , A., Ovdenko , A., Varzin , S., & Dulaev , D. (2025). Infectious complications in traumatology and orthopedics. Vestnik of Saint Petersburg University. Medicine, 19(4), 344–353. https://doi.org/10.21638/spbu11.2024.405

Issue

Section

Surgery