Postoperative cognitive dysfunction in patients of the elderly and old age operated for composition of objective cancer

Авторы

  • Николай Глушков North-Western State Medical University named after I. I. Mechnikov, 41, Kirochnaya ul., St. Petersburg, 191015, Russian Federation
  • Тимофей Горшенин North-Western State Medical University named after I. I. Mechnikov, 41, Kirochnaya ul., St. Petersburg, 191015, Russian Federation; St. Petersburg Hospital for War Veterans, 21, ul. Narodnaya, St. Petersburg, 193079, Russian Federation
  • Мария Привалова North-Western State Medical University named after I. I. Mechnikov, 41, Kirochnaya ul., St. Petersburg, 191015, Russian Federation ; St. Petersburg Hospital for War Veterans, 21, ul. Narodnaya, St. Petersburg, 193079, Russian Federation
  • Григорий Гугалев City Polyclinic no. 43, 123, Leninsky pr., St. Petersburg, 198207, Russian Federation
  • Сабина Дулаева North-Western State Medical University named after I. I. Mechnikov, 41, Kirochnaya ul., St. Petersburg, 191015, Russian Federation ;St. Petersburg Hospital for War Veterans, 21, ul. Narodnaya, St. Petersburg, 193079, Russian Federation

DOI:

https://doi.org/10.21638/spbu11.2021.104

Аннотация

The problem of preserving the quality of life in the postoperative period, one of the criteria of which is the cognitive function, retains its relevance. In patients with advanced and senile age, after undergoing surgery, cognitive disorders are swept aside, which, according to various authors, reaches 64 %. Postoperative cognitive dysfunction was studied in 168 elderly and elderly patients operated on for complications of colon cancer. Patients were divided into two groups. Patients of the control group were operated on operations conventionally, the main one — laparoscopically, using endovideosurgical technologies. Cognitive status was assessed before the operation, as well as on the first, third and seventh days of the postoperative period
using the MMSE test (abbr. English Mini Mental State Examination). The incidence of postoperative cognitive dysfunction in both groups was traced. In the development of postoperative cognitive disorders, along with such factors as general anesthesia, age, aggravated neurological history, depressive disorders, operative trauma plays an important role. The use of endoscopic technologies allows reliably reducing the risk of postoperative cognitive impairment, which in turn has a beneficial effect on the postoperative period.

Ключевые слова:

colon cancer, cognitive dysfunction, surgical treatment, postoperative period, elderly and old age

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References

Novikov A. Yu., Kovalev V. A., Vinichuk N. V., Chernykh Yu. A., Golub I. E., Sorokina L. V. Prevention and correction of cognitive impairment after general anesthesia. Zhurnal nevrologii i psikhiatrii, 2017, vol. 117, no. 6, pp. 28–31. (In Russian)

Ovezov А. М., Knyazev А. V., Pateleeva М. V. Postoperative encephalopathy: pathophysiological and morphological bases of prevention in general anesthesia. Nevrologiya, neyropsikhiatriya, psikhosomatika,2015, vol. 37, no. 2, pp. 61–66. (In Russian)

Popugaev K. A., Savin I. A., Goryachev A. S. Delirium in neuroresuscitation. II National Congress. Neotlozhnyye sostoyaniya v nevrologii. Moscow, 2011, pp. 185–191. (In Russian)

Khizhnyak A. A., Dubovskaya S. S., Mikhnevich K. G., Bausov E. A. Influence of general anesthesia on the degree of cognitive changes in elderly patients with urgent surgical pathology. Meditsina neotlozhnykh sostoyaniy,2015, vol. 5, no. 68, pp. 140–143. (In Russian)

Shchaeva S. N. Surgical treatment of colorectal cancer complicated by acute intestinal obstruction.Onkologicheskaya koloproktologiya, 2016, no. 3, pp. 8–16. (In Russian)

Chen G., Zhou Y., Shi Q., Zhou H. Comparison of early recovery and cognitive function after desflurane and sevoflurane anaesthesia in elderly patients: A meta-analysis of randomized controlled trials. Int. Med. Res., 2015, vol. 43, no. 5, pp. 619–628.

Feinkohl I., Winterer G., Spies C. D., Pischon T. Cognitive Reserve and the Risk of Postoperative Cognitive Dysfunction. Dtsch. Arztebl. Int., 2017, vol. 114, no. 7, pp. 110–117.

Krings M., Hollig A., Liu J., Grusser L., Rossaint R., Coburn M. Desflurane impairs outcome of organotypic hippocampal slices in an in vitro model of traumatic brain injury. Med. Gas. Res., 2016, vol. 6, no. 1, pp. 3–9.

Загрузки

Опубликован

01.04.2021

Как цитировать

Глушков, Н. ., Горшенин, Т., Привалова, М., Гугалев, Г., & Дулаева, С. (2021). Postoperative cognitive dysfunction in patients of the elderly and old age operated for composition of objective cancer. Вестник Санкт-Петербургского университета. Медицина, 16(1), 37–42. https://doi.org/10.21638/spbu11.2021.104

Выпуск

Раздел

Хирургия