Ultrasound and morphological parallels in assessing the state of the immune system organs in children with immune deficiency

Authors

  • Olga Vozgoment Diagnostic Radiology Department of Central Research Institute of Stomatology and Maxillofacial Surgery, 16, ul. Timura Frunze, Moscow, 119021, Russian Federation ; Children’s Radiological Diagnostics Department of Russian Medical Academy of Continuing Professional Education, 2/1, ul. Barrikadnaya, Moscow, 125993, Russian Federation
  • Andrey Nadtochiy Diagnostic Radiology Department of Central Research Institute of Stomatology and Maxillofacial Surgery, 16, ul. Timura Frunze, Moscow, 119021, Russian Federation
  • Nina Zaytseva Federal Scientific Center for Medical and Preventive Health Risk Management Technologies, 82, ul. Monastirskaya, Perm, 614045, Russian Federation
  • Elena Patlusova Perm State Medical University named after Academician E.A.Wagner, 26, ul. Petropavlovskaya, Perm, 614000, Russian Federation

DOI:

https://doi.org/10.21638/spbu11.2019.432

Abstract

The diagnosis of immune disorders is still a very difficult task. This study was performed to determine of the diagnostic ultrasound possibilities in identifying the signs of immune deficiency in children. According to the results, an increase in the spleen mass coefficient occurs with the growth in the number and size of lymphoid follicles. This is confirmed by both morphological and ultrasound data. An increase of the spleen mass coefficient in children with chronic immune-endocrine insufficiency is a reflection of system changes, which, for the most part, are manifested by hyperplastic (in few cases — involutive) processes in lymphoid organs and tissues. The technique of ultrasound examination of the spleen and neck and abdomen lymph nodes can be a non-invasive method for identifying children with immune deficiency and those risky for the development of fatal complications.

Keywords:

spleen, ultrasonography, lymphoid organs, immune deficiency

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References


References

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Shoenfeld Y., Meroni P.L., Churilov L.P. (Eds). Guide in Autoimmune Diseases for General Medical Practice. St-Petersburg, Elbi-SPb. Publ., 2017. (In Russian)

Doria A., Daneman A., Moineddin R. et al. High-frequency Sonographic Patterns of the Spleen in Children. Radiology, 2006, no. 240 (3), pp. 821–897.

Tarantino G., Scalera A., Finelli C. Liver-spleen Axis: Intersection Between Immunity, Infections and Metabolism. World J.Gastroenterol., 2013, no. 19 (23), pp. 3534–3542.

Vozgoment O.V. Ultrasonic evaluation of the immune system peripheral organs condition in children under various technogenic exposure. D. Sci. Thesis (Moscow), 2015. (In Russian)

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Published

2020-06-15

How to Cite

Vozgoment, O., Nadtochiy , A., Zaytseva , N., & Patlusova , E. . (2020). Ultrasound and morphological parallels in assessing the state of the immune system organs in children with immune deficiency. Vestnik of Saint Petersburg University. Medicine, 14(4), 377–381. https://doi.org/10.21638/spbu11.2019.432

Issue

Vol. 14 No. 4 (2019)

Section

Pediatrics

License

Articles of "Vestnik of Saint Petersburg University. Medicine" are open access distributed under the terms of the License Agreement with Saint Petersburg State University, which permits to the authors unrestricted distribution and self-archiving free of charge.