Power to dissolve the bone: Autoinflammation behind the curtain. An update on chronic recurrent multifocal osteomyelitis with clinical case presentation

Авторы

  • Елена Жолобова I.M. Sechenov First Moscow State Medical University (Sechenov University), 8, Trubetskaya ul., Moscow, 119991, Russian Federation
  • Екатерина Попова I.M. Sechenov First Moscow State Medical University (Sechenov University), 8, Trubetskaya ul., Moscow, 119991, Russian Federation

DOI:

https://doi.org/10.21638/spbu11.2019.433

Аннотация

Multifaceted presentation of rheumatic diseases makes patients to consult physicians of various medical specialties, including surgeons. In this paper we present a case of pediatric patient with chronic recurrent multifocal osteomyelitis — an autoinflammatory bone disorder — who was misdiagnosed a lot and thus improperly treated before coming to the rheumatologist. An extensive review of scientific papers on chronic recurrent multifocal osteomyelitis was also conducted to show recent advances in the disease imaging and treatment. Our case illustrates that autoimmune and autoinflammatory disorders are not solely the matter of rheumatologist’s concern. Physicians of different specialties, including surgeons, should be aware of miscellaneous clinical signs of rheumatic conditions to propel their prompt, accurate diagnosis and efficient treatment.

Ключевые слова:

autoinflammatory disorders, chronic recurrent multifocal osteomyelitis (CRMO), misdiagnosis, clinical case

Скачивания

Данные скачивания пока недоступны.
 

Библиографические ссылки


References

Van Kempen T. S., Wenink M.H., Leijten E., Radstake T., Boes M. Perception of Self: Distinguishing Autoimmunity from Autoinflammation. Nature Reviews. Rheumatology, 2015, vol. 11, pp. 483–492.

Hofmann S.R., Kapplush F., Girschick H.J., Morbach H., Pablik J., Ferguson P.J., Hedrich C.M. Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment.Current Osteoporosis Reports, 2017, vol. 15, pp. 542–554.

Taddio A., Zennaro F., Pastore S., Cimaz R. An Update on the Pathogenesis and Treatment of Chronic Recurrent Multifocal Osteomyelitis in Children. Pediatric Drugs, 2017, vol. 19, pp. 165–172.

Jansson A., Renner E.D., Ramser J., Mayer A., Haban M., Meindl A., Grote V., Diebold J., Jannson V., Schneider K., Belihradsky B.H. Classification of Non-Bacterial Osteitis: Retrospective study of clinical, immunological and genetic aspects in 89 patients. Rheumatology, 2007, vol. 46, no. 1, pp. 154–160.

Kopchak O.L., Kostik M.M., Mushkin A.Yu. Chronic Non-Bacterial (“Sterile”) Osteomyelitis in the Practice of Pediatric Rheumatologist, the Contemporary Diagnostic and Treatment Approaches: Literature Review and Own Data Analysis. Voprosy sovremennoi pediatrii, 2016, vol. 15, no. 1, pp. 33–44. (In Russian)

Zholobova E. S., Popova E.Yu. Modern View on Chronic Recurrent Multifocal Osteomyelitis.Pediatria, 2019, vol. 98, no. 3, pp. 234–241. (In Russian)

Загрузки

Опубликован

15.06.2020

Как цитировать

Жолобова, Е., & Попова, Е. (2020). Power to dissolve the bone: Autoinflammation behind the curtain. An update on chronic recurrent multifocal osteomyelitis with clinical case presentation. Вестник Санкт-Петербургского университета. Медицина, 14(4), 382–387. https://doi.org/10.21638/spbu11.2019.433

Выпуск

Раздел

Хирургия