Integrated model for the risk assessment of the unfavourable course of binodal pathology in children

Authors

  • Елена Сергеевна Васичкина Almazov National Medical Research Centre, 2, ul. Akkuratova, St. Petersburg, 197341, Russian Federation
  • Татьяна Михайловна Первунина Almazov National Medical Research Centre, 2, ul. Akkuratova, St. Petersburg, 197341, Russian Federation
  • Татьяна Кимовна Кручина Almazov National Medical Research Centre, 2, ul. Akkuratova, St. Petersburg, 197341, Russian Federation ; St. Petersburg State Pediatric Medical University, 2, Litovskaya ul., St. Petersburg, 197341, Russian Federation
  • Дмитрий Федорович Егоров Pavlov First St. Petersburg State Medical University, 6–8, ul. L’va Tolstogo, St. Petersburg, 197022, Russian Federation
  • Дмитрий Сергеевич Лебедев Almazov National Medical Research Centre, 2, ul. Akkuratova, St. Petersburg, 197341, Russian Federation

DOI:

https://doi.org/10.21638/11701/spbu11.2018.204

Abstract

The article presents a model the risk assessment of the unfavorable course of binodal pathology in children. We enrolled 177 consecutive patients with binodal pathology. In the analysis of complaints, clinical picture and data of electrocardiographic and electrophysiological parameters, factors that influenced the course of the binodal pathology were established. Risk factors were: male gender, the age of manifestation of the disease over 14.5 years, the minimum heart rate is less than 52 beats per minute (before the medication), the value of SNRT more than 1510 ms (before the test with atropine), the minimum heart rate after the administration of atropine is less than 96 bpm. The total risk score is calculated as the sum of the values of these indicators (5 risk factors) and can take values from 0 to 5 points. Three levels of total risk score are singled out: 0 points — low probability of negative dynamics; 1–3 points — an insignificant
probability of negative dynamics; 4–5 points — significant risk of negative dynamics.

Keywords:

binodal disease, children, electrophysiological study, risk factors, he adverse prognosis, the adverse prognosis

Downloads

Download data is not yet available.
 

References

Литература

James T. N. Structure and function of the sinus node, AV node and his bundle of the human heart:Part I — Structure // Progr. Cardiovasc. Dis. 2002. Vol. 45. P. 235–267.

Jongbloed M. R., Mahtab E. A., Blom N. A., Schalij M. J., Gittenberger-de Groot A. C. Development of the cardiac conduction system and the possible relation to predilection sites of arrhythmogenesis // Sci. World J. 2008. Vol. 8. P. 239–269.

Lown B. Electrical reversion of cardiac arrhythmias // Brit. Heart J. 1967. Vol. 29. P. 469.

Kaplan B. M., Langendorf R., Lev M., Pick A. Tachycardia-bradycardia syndrome (“so-called sick sinus syndrome”) // Am. J. Cardiol. 1973. Vol. 31. P. 497–508.

Васичкина Е. С., Кручина Т. К., Первунина Т. М., Егоров Д. Ф., Эрман М. В. Сочетанное поражение синусового узла и атриовентрикулярного соединения у детей. Клиническая и электрофизиологическая характеристики и течение бинодальной патологии // Вестн. С.-Петерб.

унта.

Васичкина Е. С., Кручина Т. К., Лебедев Д. С., Егоров Д. Ф. Вегетативная бинодальная дисфункция у детей. Особенности естественного течения // Казанский медицинский журнал. 2015.Т. 96, вып. 4. С. 609–615.

Васичкина Е. С., Кручина Т. К., Первунина Т. М., Егоров Д. Ф., Лебедев Д. С. Клинико-электрофи-зиологическое течение бинодальной болезни у детей с имплантированными электрокардиостимуляторами // Практическая медицина. 2017. № 2 (103). C. 78–81.

Васичкина Е. С. Совершенствование подходов к диагностике и лечению жизнеопасных нарушений ритма и проводимости сердца у детей: автореф. дис. … д-ра мед. наук. СПб., 2016. 36 с.

Реброва О. В. Статистический анализ медицинских данных с помощью пакета программ «Статистика». М.: Медиа Сфера, 2002. 380 с.

Юнкеров В. И., Григорьев С. Г. Математико-статистическая обработка данных медицинских исследований. Лекции для адъюнктов и аспирантов. СПб., 2005. 266 с.


References

James T. N. Structure and function of the sinus node, AV node and his bundle of the human heart:Part I — Structure.Progr. Cardiovasc. Dis., 2002, vol. 45, pp. 235–267.

Jongbloed M. R., Mahtab E. A., Blom N. A., Schalij M. J., Gittenberger-de Groot A. C. Development of the cardiac conduction system and the possible relation to predilection sites of arrhythmogenesis. Sci.

World J., 2008, vol. 8, pp. 239–269.

Lown B. Electrical reversion of cardiac arrhythmias. Brit. Heart J., 1967, vol. 29, p. 469.

Kaplan B. M., Langendorf R., Lev M., Pick A. Tachycardia-bradycardia syndrome (“so-called sick sinus syndrome”). Am. J. Cardiol., 1973, vol. 31, pp. 497–508.

Vasichkina E. S., Kruchina T. K., Pervunina T. M., Egorov D. F., Erman M. V. Sochetannoe porazhenie sinusovogo uzla i atrioventrikuliarnogo soedineniia u detei. Klinicheskaia i elektrofiziologicheskaia

kharakteristiki i techenie binodal’noi patologii [Combined distyrbance of the sino-atrial node and

atrioventricular node in children. Clinical and electrophysiological characteristics of binodal pathology].

Vestnik of Saint Petersburg University. Series 11. Medicine, 2012, issue 2, pp. 58–67. (In Russian)

Vasichkina E. S., Kruchina T. K., Lebedev D. S., Egorov D. F. Vegetativnaia binodal’naia disfunktsiia u detei. Osobennosti estestvennogo techeniia [Hypervagatonic binodal dysfunction in children. The

natural history of binodal dysfunction]. Kazan Medical Journal. Series 11, 2015, vol. 96, pp. 609–615.

(In Russian)

Vasichkina E. S., Kruchina T. K., Pervunina T. M., Egorov D. F., Lebedev D. S. Kliniko-elektrofiziologicheskoe techenie binodal’noi bolezni u detei s implantirovannymi elektrokardiostimuliatorami

[Clinical course and electrophysiological characteristics of binodal desease at children with implanted

pacemakers]. Practical Medicine, 2017, no. 2 (103), pp. 78–81. (In Russian)

Vasichkina E. S. Sovershenstvovanie podkhodov k diagnostike i lecheniiu zhizneopasnykh narushenii ritma i provodimosti serdtsa u detei: avtoref. dis. … d-ra med. nauk [Perfection of approaches to

diagnostics and treatment of life-threatening rhythm disturbances and heart conduction in children.

Thesis of MD Diss.]. St. Petersburg, 2016. 36 p. (In Russian)

Rebrova O. V. Statisticheskii analiz meditsinskikh dannykh s pomoshch’iu paketa programm “Statistika” [Statistical analysis of medical data using the “Statistic” software package]. Мoscow, Media Sphere Pub., 2002. 380 p. (In Russian).

Iunkerov V. I., Grigor’ev S. G. Matematiko-statisticheskaia obrabotka dannykh me-ditsinskikh issledovanii. Lektsii dlia ad”iunktov i aspirantov [Mathematico-statistical processing of medical research data. Lectures for adjuncts and graduate students]. St. Petersburg, 2005. 266 p. (In Russian)

Published

2018-06-29

How to Cite

Васичкина, Е. С., Первунина, Т. М., Кручина, Т. К., Егоров, Д. Ф., & Лебедев, Д. С. (2018). Integrated model for the risk assessment of the unfavourable course of binodal pathology in children. Vestnik of Saint Petersburg University. Medicine, 13(2), 164–173. https://doi.org/10.21638/11701/spbu11.2018.204

Issue

Section

Pediatrics