Cognitive disorders in ovarian cancer patients (literature review)
DOI:
https://doi.org/10.21638/11701/spbu11.2018.306Abstract
The article provides a review of cognitive impairment in oncology patients basing on the example of ovarian cancer women. Consecutive steps in the research for neuropsychological assessment of cancer patient with non-CNS tumors are demonstrated, including currently existing cognitive studies for oncogynecological patients. The suspected reasons for cognitive impairment at different treatment stages are being analyzed with the focus on cognitive dysfunction in the group of ovarian cancer patients. It is being discussed in the article that besides of the neurotoxic influence of chemo treatment, cognitive functions of the ovarian cancer patients can be impaired due to various other factors and that the subjective assessment of cognitive functioning does not correspond to the objective results of the neuropsychological assessment. It is stated in the article that at the moment there is no uniform methodological approach for neuropsychological assessment of ovarian cancer patients and multidisciplinary platform is required including the use of EEG, MRI and fMRI methods for precise evaluation of subtle cognitive impairments.
Keywords:
ovarian cancer, cognitive function, neuropsychological assessment, central nervous system, quality of life, affective disorders
Downloads
Download data is not yet available.
References
Литература
Schagen S. B., Hamburger H. L., Muller M. J. et al. Neurophysiological evaluation of late effects of adjuvant thigh dose chemotherapy on cognitive function // J. оf Neurooncology. 2001. N 51(2). P. 159–65.
Wefel J. S., Vardy J., Ahles T. A. et al. International Cognition and Cancer Task Force recommendations to harmonise studies of cognitive function in cancer patients // Lancet Oncology. 2011. Vol. 12. P. 703–708.
Myers J. S. Chemotherapy-related cognitive impairment: neuroimaging, neuropsychological testing, and the neuropsychologist // Clin. J. of Oncololy Nursing. 2009. N 13. P. 413–21.
Correa D. D., Hess L. M. Cognitive function and quality of life in ovarian cancer // Gynecol. Oncol. 2014. N 124 (3). P. 404–409.
Lutgendorf S. K., Slavich G. M., DeGeest K., Goodheart M., Bender D., Thaker P. H., Penedo F., Zimmerman B., Lucci J., Mendez L. Collins K., Sood A. K. Non-cancer life stressors contribute to impaired quality of life in ovarian cancer patients // Gynecol. Oncology. 2013. N 131. P. 667–673.
Жорданиа К. И., Хохлова С. В. Ранний рак яичников: наш взгляд на проблему // Опухоли женской репродуктивной системы. 2011. № 3. С. 56–64.
Каприн А. Д., Старинский В. В., Петрова Г. В. Злокачественные новообразования в России в 2015 г. (заболеваемость и смертность) / МНИОИ им. П. А. Герцена, филиал ФГБУ «НМИРЦ» Минздрава России. М., 2017. 250 с.
Савинова А. Р., Гатауллин И. Г. Индивидуальный подход к лечению рака яичников // Казанский медицинский журнал. 2016. Т. 97, № 3. С. 388–393.
Hodgson K. D., Hutchinson A. D., Wilson C. J., Nettelbeck T. A meta-analysis of the effects of chemotherapy on cognition in patients with cancer // Cancer Treatment Reviews. 2013. N 39. P. 297–304.
Oxman T. E., Silberfarb P. M. Serial cognitive test in gin cancer patients receiving chemotherapy // Amer. J. of Psychiatry. 1980. N 137. P. 1263–1265.
Ahles T. A., Correa D. D. Neuropsychological impact of cancer and cancer treatments, in Holland // J. C. Psycho-Oncology (ed 2). New York: Oxford University Press, 2010. P. 251–257.
Correa D. D., Zhou Q., Thaler H. T., Maziarz M., Hurley K., Hensley M. L. Cognitive functions in longterm survivors of ovarian cancer // Gynecol. Oncol. 2010. N 119 (2). P. 366–369.
Федорова С. Ю., Хрущев С. О., Выборных Д. Э. Когнитивные нарушения при трансплантации костного мозга (обзор литературы) // Обозрение психиатрии и медицинской психологии. 2017. № 4. С. 18–26.
Ahles T. A., Saykin A. J. Breast cancer chemotherapy-related cognitive dysfunction // Clin. Breast Cancer. 2002. Vol. 3, supplement 3. P. S84-S90.
Koppelmans V., Breteler M. M. B., Boogerd W., Seynaeve C., Gundy C., Schagen S. B. Neuropsychological performance in survivors of breast cancer more than 20 years after adjuvant chemotherapy // J. of Clin. Oncology. 2012. Vol. 30(10). P. 1080–1086.
Nguyen C. M., Yamada T. H., Beglinger L. J., Cavanaugh J. E., Denburg N. L., Schultz S. K. Cognitive features 10 or more years after successful breast cancer survival: comparisons across types of cancer interventions // Psychooncology. 2013. Vol. 22(4). P. 862–868.
Schagen S. B., MullerM. J., Boogerd W., Mellenbergh G. J., VanDam F. S. Change in cognitive function after chemotherapy: a prospective longitudinal study in breast cancer patients // J. of the National CancerInstitute. 2006. N 98(23). P. 1742–1745.
Yamada T. H., Denburg N. L., Beglinger L. J., Schultz S. K. Neuropsychological outcomes of older breast cancer survivors: cognitive feature stenor more years after chemotherapy // J. of Neuropsychiatry Clin. Neuroscience. 2010. 22(1). P. 48–54.
Tannock I. F., Ahles T. A., Ganz P. A. et al. Cognitive impairment associated with chemotherapy for cancer: Report of a workshop // J. of Clin. Oncology. 2004. 22. P. 2233–2239.
Vardy J., Wefel J. S., Ahles T. A. et al. Cancer and cancer-therapy related cognitive dysfunction: An international perspective from the Venice Cognitive Workshop // Annals of Oncology. 2008. Vol. 19. P. 623–629.
Ono Miyuki, Ogilvie J. M., Wilson J. S., Green H. J., Chambers S. K., Ownsworth T., Shum D. H. K. A meta-analysis of cognitive impairment and decline associated with adjuvant chemotherapy in women with breast cancer // Frontiers in Oncology. 2015. Vol. 5. P. 1–19.
Shuster L. T., Gostout B. S., Grossardt B. R., Rocca W. A. Prophylactic oophorectomy in pre-menopausal women and long term health — a review // Menopause International. 2008. N 14 (3). P. 111–116.
Ahles T. A., James C., Root and Elizabeth L. Ryan. Cancer- and Cancer Treatment —Associated Cognitive Change: An Update on the State of the Science // J. of Clin. Oncol. 2012. N 30. P. 3675–3686.
Ahles T. A., Saykin A. J., McDonald B. C. et al. Cognitive function in breast cancer patients prior to adjuvant treatment // Breast Cancer Res. and Treat. 2008. N 110 (1). P. 143–152.
Janelsins M. C., Kesler S. R., Ahles T. A., Morrow G. R. Prevalence, mechanisms, and management of cancer-related cognitive impairment // Intern. Rev. of Psychiatry. 2014. N 26(1). P. 102–113.
Wefel J. S., Lenzi R., Theriault R. et al. Chemobrain in breast carcinoma? A prologue // Cancer. 2004. Vol. 101. P. 466–475.
Петрова Н. Н., Белозёр А. С. Оценка когнитивных и аффективных нарушений на различных этапах лечения рака яичников // Школа В. М. Бехтерева: от истоков до современности: материалы Всероссийской научно-практической конференции с международным участием, посвященной 160-летию со дня рождения Владимира Михайловича Бехтерева и 110-летию Санкт-Петербургского научно-исследовательского психоневрологического института им. В. М. Бехтерева. [Электронное издание]. СПб.: Альта Астра, 2017. С. 147–148.
Hurria A., Somlo G., Ahles T. Renaming “chemobrain” // Cancer Invest. 2007. N 25 (6). P. 373–377.
Janelsins M. C., Kesler S. R., Ahles T. A., Morrow G. R. Prevalence, mechanisms, and management of cancer-related cognitive impairment // International Review of Psychiatry. 2014. N 26(1). P. 102–113.
Bender C. M., Sereika S. M., Berga S. L., Vogel V. G., Brufsky A. M., Paraska K. K., Ryan C. M. Cognitive impairment associated with adjuvant therapy in breast cancer // Psychooncology. 2006. N 15. P. 422–430.
Dwek M. R., Rixon L., Hurt C., Simon A., Newman S. Is there a relationship between objectively measured cognitive changes in patients with solid tumours undergoing chemotherapy treatment and their healthrelated quality of life outcomes? A systematic review // Psychooncology. 2017. Vol. 26. P. 1422–1432.
Asher A., Myers J. S. The Effect of Cancer Treatment on Cognitive Function. Clin. Advances in Hematology & Oncology. 2015. Vol. 13 (7). P. 441–450.
Белозёр А. С., Петрова Н. Н. Субъективное восприятие и объективное исследование когнитивных нарушений у больных раком яичников // Материалы XVII научно-практической конференции «Актуальные проблемы психосоматики в общемедицинской практике» (15 ноября 2017 года, Санкт-Петербург) / под ред. акад. РАН Мазурова В. И. СПб., 2017. С. 13–16.
Wagner L., Sweet J., Butt Z., Lai J., Cella D. Measuring patient self-reported cognitive function: development of the functional assessment of cancer therapy cognitive function instrument // The J. of Supportive Oncology. 2009. N. 7. P. W32–W39.
Mayerhofer K., Bodner-Adler B., Bodner K. et al. A paclitaxel-containing chemotherapy does not cause central nervous adverse effects: a prospective study in patients with ovarian cancer // Anticancer Research. 2000. N 20. P. 4051–4055.
Kudelka A. P. et al. Phase II study of i. v. CI-980 in patients with advanced platinum refractory epithelial ovarian carcinoma // Anti-Cancer Drugs. 1998. Vol. 9, N. 5. P. 405–409.
Hensley M. L., Correa D. D., Thaler H., Wilton A., Venkatraman E., Sabbatini P., Chi D. S., Dupont J., Spriggs D., Aghajanian C. Phase I/II study of weekly paclitaxel plus carboplatin and gemcitabine as first-line treatment of advanced-stage ovarian cancer: Pathologic complete response and longitudinal assessment of impact on cognitive functioning // Gynecol. Oncology. 2006. N 102(2). P. 270–277.
Hess L. M., Huang H. Q., Hanlon A. L., Robinson W. R., Johnson R., Chambers S. K., Mannel R. S., Puls L., Davidson S. A., Method M., Lele S., Havrilesky L., Nelson T., Alberts D. S. Cognitive function during and six months following chemotherapy for front-line treatment of ovarian, primary peritoneal or fallopian tube cancer: An NRG oncology/gynecologic oncology group study // Gynecol. Oncology. 2015. N 139 (3). P. 541–545.
References
Schagen S. B., Hamburger H. L., Muller, M. J. et al. Neurophysiological evaluation of late effects of adjuvant thigh dose chemotherapy on cognitive function. J. оf Neurooncology, 2001, vol. 51(2), pp. 159–165.
Wefel J. S., Vardy J., Ahles T. A. et al. International Cognition and Cancer Task Force recommendations to harmonise studies of cognitive function in cancer patients. Lancet Oncology, 2011, vol. 12, pp. 703–708.
Myers J. S. Chemotherapy-related cognitive impairment: neuroimaging, neuropsychological testing, and the neuropsychologist. Clin. J. of Oncololy Nursing, 2009, no. 13, pp. 413–421.
Correa D. D., Hess L. M. Cognitive function and quality of life in ovarian cancer. Gynecol. Oncol., 2014, no. 124 (3), pp. 404–409.
Lutgendorf S. K., Slavich G. M., DeGeest K., Goodheart M., Bender D., Thaker P. H., Penedo F., Zimmerman B., Lucci J., Mendez L. Collins K., Sood A. K. Non-cancer life stressors contribute to impaired quality of life in ovarian cancer patients. Gynecol. Oncology, 2013, no. 131, pp. 667–673.
Zhordania K. I., Khokhlova S. V. Rannii rak iaichnikov: nash vzgliad na problemu m [Early ovarian cancer: our perception of this problem]. Opukholi zhenskoi reproduktivnoi sistemy, 2011, vol. 3, pp. 56–64. (In Russian)
Kaprin A. D., Starinskiy V. V., Petrova G. V. Zlokachestvennye novoobrazovaniia v Rossii v 2015 g. (zabolevaemost’ i smertnost’): [Malignant neoplasms in Russia in 2015 (incidence and mortality)]: MNIOI named after P. A. Hertzen, filial FGBU “NMIRZ” Minzdrava Rossii. Moscow, 2017. 250 p. (In Russian)
Savinova A. R., GataullinI. G. Individual’nyi podkhod k lecheniiu raka iaichnikov [Individual approach to ovarian cancer treatment]. Kazanskii meditsinskii zhurnal, 2016, vol. 97 (3), pp. 388–393. (In Russian)
Hodgson K. D., Hutchinson A. D., Wilson C. J., Nettelbeck T. A meta-analysis of the effects of chemotherapy on cognition in patients with cancer. Cancer Treatment Reviews, 2013, no. 39, pp. 297–304.
Oxman T. E., Silberfarb P. M. Serial cognitive test in gin cancer patients receiving chemotherapy. Amer. J. оf Psychiatry, 1980, no. 137, pp. 1263–1265.
Ahles T. A., Correa D. D. Neuropsychological impact of cancer and cancer treatments, in Holland. J. C. Psycho-Oncology (ed 2). New York, Oxford University Press, 2010, pp. 251–257.
Correa D. D., Zhou Q., Thaler H. T., Maziarz M., Hurley K., Hensley M. L. Cognitive functions in longterm survivors of ovarian cancer. Gynecol. Oncol., 2010, no. 119 (2), pp. 366–369.
Fedorova S. Yu., Khruschev S. O., Vybornikh D. E. Kognitivnye narusheniia pri transplantatsii kostnogo mozga (obzor literatury) [Cognitive dysfunctions in bone-marrow transplant]. Obozrenie psikhiatrii i meditsinskoi psikhologii, 2017, vol. 4, pp. 18–26. (In Russian)
Ahles T. A., Saykin A. J. Breast cancer chemotherapy-related cognitive dysfunction. Clin. Breast Cancer, 2002, vol. 3, supplement 3, pp. S84–S90.
Koppelmans V., Breteler M. M. B., Boogerd W., Seynaeve C., Gundy C., Schagen S. B. Neuropsychological performance in survivors of breast cancer more than 20 years after adjuvant chemotherapy. J. of Clin. Oncology, 2012, vol. 30(10), pp. 1080–1086.
Nguyen C. M., Yamada T. H., Beglinger L. J., Cavanaugh J. E., Denburg N. L., Schultz S. K. Cognitive features 10 or more years after successful breast cancer survival: comparisons across types of cancer interventions. Psychooncology, 2013, no. 22(4), pp. 862–868.
Schagen S. B., MullerM. J., Boogerd W., Mellenbergh G. J., VanDam F. S. Change in cognitive function after chemotherapy: a prospective longitudinal study in breast cancer patients. J. of the National Cancer Institute, 2006, no. 98(23), pp. 1742–1745.
Yamada T. H., Denburg N. L., Beglinger L. J., Schultz S. K. Neuropsychological outcomes of older breast cancer survivors: cognitive feature stenor more years after chemotherapy. J. of Neuropsychiatry Clin. Neuroscience, 2010, vol. 22(1), pp. 48–54.
Tannock I. F., Ahles T. A., Ganz P. A. et al. Cognitive impairment associated with chemotherapy for cancer: Report of a workshop. J. of Clin. Oncology, 2004, vol. 22, pp. 2233–2239.
Vardy J., Wefel J. S., Ahles T. A. et al. Cancer and cancer-therapy related cognitive dysfunction: An international perspective from the Venice Cognitive Workshop. Annals of Oncology, 2008, vol. 19, pp. 623–629.
Ono Miyuki, Ogilvie J. M., Wilson J. S., Green H. J., Chambers S. K., Ownsworth T., Shum D. H. K. A meta-analysis of cognitive impairment and decline associated with adjuvant chemotherapy in women with breast cancer. Frontiers in Oncology, 2015, vol. 5, pp. 1–19.
Shuster L. T., Gostout B. S., Grossardt B. R., Rocca W. A. Prophylactic oophorectomy in pre-menopausal women and long term health — a review. Menopause International, 2008, no. 14 (3), pp. 111–116.
Ahles T. A., James C., Root and Elizabeth L. Ryan. Cancer- and Cancer Treatment–Associated Cognitive Change: An Update on the State of the Science. J. of Clin. Oncol., 2012, no. 30, pp. 3675–3686.
Ahles T. A., Saykin A. J., McDonald B. C. et al: Cognitive function in breast cancer patients prior to adjuvant treatment. Breast Cancer Res. and Treat., 2008, no. 110 (1), pp. 143–152.
Janelsins M. C., Kesler S. R., Ahles T. A., Morrow G. R. Prevalence, mechanisms, and management of cancer-related cognitive impairment. Intern. Rev. of Psychiatry, 2014, no. 26(1), pp. 102–113.
Wefel J. S., Lenzi R., Theriault R. et al. Chemobrain in breast carcinoma? A prologue. Cancer, 2004, vol. 101, pp. 466–475.
Petrova N. N., Belozer A. S. Otsenka kognitivnykh i affektivnykh narushenii na razlichnykh etapakh lecheniia raka iaichnikov [Assessment of cognitive and affective disorders in ovarian cancer patients at different treatment stages]. Shkola V. M. Bekhtereva: ot istokov do sovremennosti materialy Vserossiiskoi nauchno-prakticheskoi konferentsii s mezhdunarodnym uchastiem, posviashchennoi 160-letiiu so dnia rozhdeniia Vladimira Mikhailovicha Bekhtereva i 110-letiiu Sankt-Peterburgskogo nauchnoissledovatel’skogo psikhonevrologicheskogo instituta im. V. M. Bekhtereva. [Elektronnoe izdanie], 2017, pp. 147–148. (In Russian)
Hurria A., Somlo G., Ahles T. Renaming “chemobrain”. Cancer Invest., 2007, no. 25 (6), pp. 373–377.
Janelsins M. C., Kesler S. R., Ahles T. A., Morrow G. R. Prevalence, mechanisms, and management of cancer-related cognitive impairment. International Review of Psychiatry, 2014, no. 26(1), pp. 102–113.
Bender C. M., Sereika S. M., Berga S. L., Vogel V. G., Brufsky A. M., Paraska K. K., Ryan C. M. Cognitive impairment associated with adjuvant therapy in breast cancer. Psychooncology, 2006, no. 15, pp. 422–430.
Dwek M. R., Rixon L., Hurt C., Simon A., Newman S. Is there a relationship between objectively measured cognitive changes in patients with solid tumours undergoing chemotherapy treatment and their health-related quality of life outcomes? A systematic review. Psychooncology, 2017, vol. 26, pp. 1422–1432.
Asher A., Myers J. S. The Effect of Cancer Treatment on Cognitive Function. Clin. Advances in Hematology & Oncology, 2015, vol. 13 (7), pp. 441–450.
Belozer A. S., Petrova N. N. Sub”ektivnoe vospriiatie i ob”ektivnoe issledovanie kognitivnykh narushenii u bol’nykh rakom iaichnikov [Subjective perception and objective assessment of cognitive disfunctions in ovarian cancer patients]. Materialy XVII nauchno-prakticheskoi konferentsii «Aktual’nye problemy psikhosomatiki v obshchemeditsinskoi praktike» (15 noiabria 2017 goda, Sankt-Peterburg) / sbornik nauchnykh statei pod obshchei redaktsiei akad. RAN Mazurova. St. Petersburg, 2017, pp. 13–16. (In Russian)
Wagner L., Sweet J., Butt Z., Lai J., Cella D. Measuring patient self-reported cognitive function: development of the functional assessment of cancer therapy cognitive function instrument. The J. of Supportive Oncology, 2009, vol. 7, pp. W32–W39.
Mayerhofer K., Bodner-Adler B., Bodner K. et al. A paclitaxel-containing chemotherapy does not cause central nervous adverse effects: a prospective study in patients with ovarian cancer. Anticancer Research, 2000, no. 20, pp. 4051–4055.
Kudelka, A. P. et al. Phase II study of i. v. CI-980 in patients with advanced platinum refractory epithelial ovarian carcinoma. Anti-Cancer Drugs, 1998, vol. 9, no. 5, pp. 405–409.
Hensley M. L., Correa D. D., Thaler H., Wilton A., Venkatraman E., Sabbatini P., Chi D. S., Dupont J., Spriggs D., Aghajanian C. Phase I/II study of weekly paclitaxel plus carboplatin and gemcitabine as first-line treatment of advanced-stage ovarian cancer: Pathologic complete response and longitudinal assessment of impact on cognitive functioning. Gynecol. Oncology, 2006, no. 102(2), pp. 270–277.
Hess L. M., Huang H. Q., Hanlon A. L., Robinson W. R., Johnson R., Chambers S. K., Mannel R. S., Puls L., Davidson S. A., Method M., Lele S., Havrilesky L., Nelson T., Alberts D. S. Cognitive function during and six months following chemotherapy for front-line treatment of ovarian, primary peritoneal or fallopian tube cancer: An NRG oncology/gynecologic oncology group study. Gynecol. Oncology, 2015, no. 139 (3), pp. 541–545.
Downloads
Published
2018-09-20
How to Cite
Петрова, Н. Н., & Белозёр, А. С. (2018). Cognitive disorders in ovarian cancer patients (literature review). Vestnik of Saint Petersburg University. Medicine, 13(3), 291–300. https://doi.org/10.21638/11701/spbu11.2018.306
Issue
Section
Oncology
License
Articles of "Vestnik of Saint Petersburg University. Medicine" are open access distributed under the terms of the License Agreement with Saint Petersburg State University, which permits to the authors unrestricted distribution and self-archiving free of charge.
